Medical Treatments for Crohn's Disease
Evidence-based information on Crohn's disease treatments including biologics, steroids, surgery, antibiotics, and the latest medical research from the IBD community.
82 articles
Entyvio vs Skyrizi for Crohn's Disease: A Patient Comparison
Entyvio vs Skyrizi for Crohn's disease: how the two drugs work, what their trials showed, safety, dosing burden, and where 2025 AGA guidance puts each.
Rinvoq vs Stelara for Crohn's: Oral JAK or Biologic
Rinvoq vs Stelara for Crohn's disease: a daily pill or an injected biologic. What each trial showed, the boxed warning gap, dosing burden and 2026 costs.
Entyvio vs Stelara for Crohn's Disease: How They Compare
Entyvio vs Stelara for Crohn's disease: how these two biologics compare on mechanism, dosing, real-world evidence, safety and what the guidelines say.
Is Stelara Safe Long Term? 5 Years of Crohn's Evidence
Is Stelara safe long term? Here is what pooled Crohn's trial data through 5 years, registry safety, pregnancy outcomes and the FDA label actually show.
Rinvoq Side Effects in Crohn's: What Patients Actually Report
Rinvoq side effects in Crohn's: the FDA boxed warning in plain language, acne and infection rates from trials and real-world data, plus lab monitoring.
Skyrizi Cost for Crohn's: Copay Card, Assistance, Real Prices
Skyrizi cost for Crohn's: verified list price, what the Skyrizi Complete copay card really covers, options if you are uninsured, and the Medicare coverage gap.
Stelara Cost in 2026: Copay, Biosimilars and How to Pay Less
Stelara cost in 2026: the real list price, the $5 copay card terms and limits, Medicare's new negotiated price, and eight biosimilars at up to 95% off.
Entyvio Cost Without Insurance: Prices, Copay and Help
What does Entyvio cost without insurance? Verified 2026 Medicare prices, the $20,000 copay program, and Takeda's free-drug route for uninsured patients.
Blood Clots and Crohn's Disease: A Patient Safety Guide
Blood clots and Crohn's disease are closely linked. Find out when your clot risk peaks, the warning signs to watch for, and how prevention actually works.
Gallstones in Crohn's Disease: Causes and Prevention
Gallstones affect up to 14.7% of people with Crohn's disease, most often after ileal disease or surgery. Learn the causes, risk factors, and prevention.
Uveitis and Crohn's Disease: A Complete Patient Guide
Uveitis is a serious eye complication of Crohn's disease that can threaten vision. Learn the symptoms, prevalence, warning signs, and best treatments.
Combination Therapy for Crohn's: Biologic + Immunomodulator
Combination therapy for Crohn's disease pairs a biologic with an immunomodulator to boost remission rates. Learn what the SONIC and SPARE trials show.
Kono-S Anastomosis for Crohn's Disease: A Patient Guide
Kono-S anastomosis for Crohn's disease may reduce postoperative recurrence after ileocolic resection. Learn how the technique works and what evidence shows.
Sarcopenia in Crohn's Disease: Muscle Loss Explained
Sarcopenia affects up to 50% of Crohn's disease patients, raising hospitalization, surgery, and infection risk. Learn how to spot muscle loss and reverse it.
Ozempic and Crohn's Disease: A Patient Safety Guide
Considering Ozempic with Crohn's disease? Learn what 2025 research shows about GLP-1 agonist safety, weight loss benefits, flare risks, and stricture concerns.
Erythema Nodosum in Crohn's Disease: A Patient Guide
Erythema nodosum affects up to 15% of Crohn's disease patients. Learn the causes, symptoms, and evidence-based treatments for this painful skin condition.
Cimzia (Certolizumab Pegol) for Crohn's: A Patient Guide
Cimzia (certolizumab pegol) is an anti-TNF biologic for moderate-to-severe Crohn's disease. Learn dosing, efficacy, safety, and its pregnancy profile.
Mirikizumab (Omvoh) for Crohn's Disease: A Patient Guide
Mirikizumab (Omvoh) is an IL-23p19 biologic FDA-approved for moderate to severe Crohn's disease in 2025. Learn VIVID-1 trial results, dosing, and side effects.
Budesonide for Crohn's Disease: A Patient's 2026 Guide
Budesonide for Crohn's disease targets ileal inflammation with fewer side effects than prednisone. Learn dosing, efficacy, side effects, and when to use it.
Ileocecal Resection for Crohn's Disease: A Patient's Guide
What ileocecal resection involves, who needs it, hospital stay and home recovery, and the 10-year data on remission after the most common Crohn's surgery.
HLA-DQA1*05 Genetic Testing for Crohn's Disease Biologics
HLA-DQA1*05 genetic testing predicts anti-drug antibody risk in Crohn's disease patients starting Humira or Remicade. Learn what your test results mean.
Azathioprine for Crohn's Disease: A 2026 Patient Guide
Azathioprine for Crohn's disease: how it works, TPMT/NUDT15 testing, dosing, cancer and infection risks, and its evolving role in the 2025 ACG guidelines.
Methotrexate for Crohn's Disease: A Patient's 2026 Guide
Methotrexate for Crohn's disease is a steroid-sparing immunomodulator. Learn how it works, safe dosing, folic acid, side effects, and 2025 AGA guidelines.
Humira (Adalimumab) for Crohn's Disease: A Patient Guide
Humira (adalimumab) for Crohn's: how this anti-TNF works, dosing schedule, side effects, biosimilar switching, and what the latest evidence tells patients.
Omvoh (Mirikizumab) for Crohn's Disease: A Patient Guide
FDA-approved January 2025, Omvoh (mirikizumab) is a new IL-23 inhibitor for moderate-to-severe Crohn's disease. Learn how it works, safety, and results.
Tremfya (Guselkumab) for Crohn's Disease: A Patient Guide
Tremfya (guselkumab) is the first IL-23 inhibitor for Crohn's with both SC and IV induction. Trial results, dosing, side effects and how to access it.
Colon Cancer Screening in Crohn's Disease: A Patient Guide
Learn when colon cancer screening for Crohn's disease should begin, how often to get colonoscopies, and what surveillance techniques catch dysplasia early.
Best Biologic for Crohn's Disease: How to Choose
Skyrizi, Entyvio, Stelara or Rinvoq? How gastroenterologists choose a biologic for Crohn's, what head-to-head trials show, and the questions to bring.
Crohn's Disease vs Ulcerative Colitis: Key Differences
Crohn's disease vs ulcerative colitis: Crohn's can affect any part of the GI tract through all bowel-wall layers, while UC affects only the colon's lining.
IBD Medications Compared: Crohn's and Colitis Treatments
All five IBD drug groups compared in plain English: 5-ASAs, steroids, immunomodulators, biologics and small molecules, how they work and what they treat.
New IBD Treatments in 2026: What Patients Should Know
Every newly approved Crohn's and colitis treatment through 2026: IL-23 inhibitors, JAK pills, S1P modulators, Zymfentra and biosimilars, explained.
Rinvoq (Upadacitinib) for Crohn's Disease: A Patient Guide
Rinvoq (upadacitinib) is a once-daily oral JAK inhibitor for moderate-to-severe Crohn's disease. Learn how it works, the trial results, dosing, and safety risks.
Skyrizi vs Stelara for Crohn's Disease: A Patient Guide
In the SEQUENCE trial Skyrizi beat Stelara for endoscopic remission at week 48 (31.8% vs 16.2%). Dosing, safety, switching and cost compared.
Stelara (Ustekinumab) for Crohn's Disease: A Patient Guide
Stelara for Crohn's is an anti-IL-12/23 biologic given as a single weight-based IV infusion, then 90 mg under the skin every 8 weeks. Here is the evidence.
Ulcerative Colitis Symptoms: A Complete Patient Guide
Ulcerative colitis symptoms include bloody diarrhea, urgency, rectal bleeding, and cramping. Learn how they vary by location, severity, and warning signs.
Ulcerative Colitis Treatment: A Patient Guide
Ulcerative colitis treatment uses 5-ASAs, steroids, immunomodulators, biologics, and small molecules to induce and maintain remission, with surgery as a cure.
Biosimilars for Crohn's Disease: A Patient's 2026 Guide
Biosimilars for Crohn's disease are reshaping IBD care in 2026. Learn how they work, what switching studies show, and how to talk to your GI team today.
Strictureplasty for Crohn's Disease: Bowel-Sparing Surgery
Strictureplasty for Crohn's disease widens narrowed bowel without removing intestine. Learn the techniques, indications, recovery, and long-term outcomes.
Vedolizumab (Entyvio) for Crohn's Disease: A Patient Guide
Vedolizumab (Entyvio) is a gut-selective biologic for Crohn's disease. Learn how this anti-integrin therapy works, what trials show, and dosing options.
Hyperbaric Oxygen Therapy for Crohn's: A Patient Guide
Hyperbaric oxygen therapy may help heal perianal fistulas and reduce Crohn's disease inflammation. Learn how HBOT works, the evidence, and who benefits.
SIBO in Crohn's Disease: Symptoms, Diagnosis, and Treatment
SIBO affects up to 32% of Crohn's disease patients and is often mistaken for an IBD flare. Learn the symptoms, breath test diagnosis, and treatment options.
C. diff Infection in Crohn's Disease: A Patient Guide
C. diff infection hits Crohn's patients up to 10x more often. Learn how to tell a flare from infection, plus treatments like vancomycin, fidaxomicin, FMT.
Kidney Stones in Crohn's Disease: Causes and Prevention
Why Crohn's raises kidney stone risk (enteric hyperoxaluria), who is most at risk, and the prevention steps that work, starting with calcium at meals.
Bile Acid Diarrhea in Crohn's: Causes and Treatment
Bile acid diarrhea affects more than 30% of Crohn's disease patients yet often goes undiagnosed. Learn the symptoms, SeHCAT testing, and treatment options.
Endoscopic Balloon Dilation for Crohn's Strictures Guide
How balloon dilation treats Crohn's strictures without surgery: 87.6% technical success in a 2024 meta-analysis, risks, who qualifies and what to expect.
Vaccines for Crohn's Disease: What Patients Need to Know
Vaccines for Crohn's disease patients matter most before you start biologics. Learn which shots are safe, which ones to avoid, and how to time them right.
Preventing Postoperative Crohn's Recurrence: 2026 Guide
Up to half of Crohn's patients face endoscopic recurrence within a year of surgery. Learn 2026 evidence-based ways to prevent postoperative recurrence.
Capsule Endoscopy for Crohn's Disease: A Patient Guide
Capsule endoscopy for Crohn's disease uses a tiny swallowable camera to image the entire small bowel. Learn how PillCam works, what to expect, and the risks.
MR Enterography for Crohn's Disease: A Patient's Guide
MR enterography for Crohn's disease is a radiation-free scan that maps small bowel inflammation. Learn how MRE works, what to expect, and why it matters.
Top-Down vs Step-Up Therapy for Crohn's: PROFILE Trial
PROFILE trial shows top-down therapy for Crohn's disease beats step-up: 79% sustained remission vs 15% at one year. What newly diagnosed patients need to know.
Subcutaneous Infliximab (Zymfentra) for Crohn's Disease
Zymfentra lets you inject infliximab at home every two weeks after IV induction. LIBERTY-CD results, who it suits, side effects, and switching questions.
Therapeutic Drug Monitoring for Crohn's: A Patient Guide
Therapeutic drug monitoring helps Crohn's disease patients on biologics like infliximab and adalimumab stay in remission. Learn how and when TDM is used.
Fecal Calprotectin Test for Crohn's: Levels and Normal Range
Learn what your fecal calprotectin number means in Crohn's disease, with 2025 ACG and AGA cutoff guidelines and tips for tracking flares without scopes.
Stem Cell Therapy for Crohn's Disease: What Patients Should Know
Stem cell therapy shows promise for Crohn's disease, especially perianal fistulas. Learn about the latest research, types of treatment, and what to expect.
TL1A Inhibitors for Crohn's Disease: A New Drug Class
TL1A inhibitors may be the first drugs to target both inflammation and fibrosis in Crohn's. Phase 2 results, the pipeline, and when they could arrive.
JAK Inhibitors for Crohn's Disease: Real-World Results
JAK inhibitors offer a new oral treatment for Crohn's disease. Learn how upadacitinib (Rinvoq) works, real-world remission rates, and key side effects.
IL-23 Inhibitors for Crohn's Disease: What Patients Should Know
The three FDA-approved IL-23 inhibitors for Crohn's disease compared: how they work, what the trials found, side effects, and who they suit best.
Intestinal Ultrasound for Crohn's Disease: A Guide to Non-Invasive Monitoring
Intestinal ultrasound is changing how Crohn's disease is monitored. Learn how this non-invasive, radiation-free tool works and how to access it.
Could a Digital Twin of Your Gut Help Predict Crohn’s Disease Flares?
Discover how digital twin technology is transforming Crohn’s disease care by simulating gut health, predicting flares, and personalizing treatments.
Cultural Perspectives: Crohn’s Disease Diagnosis and Treatment Around the World
Explore cultural and regional differences in Crohn’s disease diagnosis and treatment around the world. Discover unique approaches to managing this chronic illness.
The Role of Gut Microbiome Diversity in Crohn’s Disease Progression and Recovery
Discover how gut microbiome diversity impacts Crohn’s disease progression and recovery. Learn the latest research and practical tips to support gut health.
Long-Term Effects of Steroid Use in Crohn’s Disease Treatment
Learn the long-term effects of steroid use in Crohn's disease treatment, including bone density loss, and discover strategies to manage these risks effectively.
The Impact of Antibiotics on Crohn's Disease
Discover the effects of antibiotics on Crohn’s disease, including risks of flare-ups and the influence on gut microbiota.
The Role of Anti-TNF Therapies in Crohn’s Disease
Learn how anti-TNF therapies work to manage Crohn’s disease by reducing inflammation, improving symptoms, and minimizing long-term damage, with a look at potential side effects.
Crohn’s Disease and Fertility: What You Need to Know
Discover how Crohn's disease and its treatments impact fertility in both men and women, and learn tips for planning a family while managing the disease.
Crohn's Disease and Heart Health: Managing Cardiovascular Risks
Learn how Crohn’s disease can increase cardiovascular risks and discover strategies for managing heart health in Crohn’s patients.
History of Crohn's Disease: Who Discovered It and When
Who discovered Crohn's disease, why it carries Burrill Crohn's name, and the 1932 paper with Ginzburg and Oppenheimer that defined it. The full story.
Crohn's Disease and Bone Health: Preventing Osteoporosis
Learn how Crohn’s disease can affect bone health and discover effective strategies for preventing osteoporosis in Crohn's patients.
Exploring the Potential of Fecal Microbiota Transplant (FMT) for Crohn's Disease
Learn about the potential of Fecal Microbiota Transplant (FMT) in managing Crohn's disease, and how gut bacteria may help reduce inflammation and restore balance.
Understanding the Genetic Factors Behind Crohn’s Disease
Discover how genetic factors contribute to the development of Crohn’s disease, including key genes linked to inflammation and immune response.
The Role of Surgery in Crohn's Disease Management: When and Why It's Needed
Learn about the role of surgery in managing Crohn's disease, including when it's necessary, the types of surgeries available, and what patients can expect.
Understanding the Connection Between Crohn's Disease and Other Autoimmune Disorders
Crohn's is not classified as autoimmune, yet it shares genes and triggers with conditions like rheumatoid arthritis. What the overlap means for you.
Crohn's Disease and Pregnancy: A Comprehensive Management Guide
Learn how to manage Crohn's disease during pregnancy. Discover key strategies for before, during, and after pregnancy to ensure the health of both mother and baby.
Is the Integration of Gastroenterology and Endocrinology Clinics Changing the Game for IBD Patients?
Discover the new era of patient care with integrated gastroenterology and endocrinology for IBD. Learn how multidisciplinary clinics enhance outcomes.
Integrating Gastroenterology and Rheumatology in IBD Care
Discover the vital role of integrating gastroenterology and rheumatology in IBD care. Learn how this holistic approach enhances patient outcomes.
Maximizing Patient Outcomes: Integrating Gastroenterology and Dermatology for IBD Care
Discover the powerful impact of integrating gastroenterology and dermatology for IBD patients. Learn how collaboration leads to better care and outcomes.
Highlights from the 2024 Crohn’s & Colitis Congress
Discover the groundbreaking advancements in IBD care at the 2024 Crohn’s & Colitis Congress. From innovative drug therapies to precision medicine, read the highlights now!
Noninvasive Monitoring: Tracking IBD with Sweat
Discover the future of IBD management with noninvasive monitoring: Tracking IBD with Sweat. Learn how sweat analysis revolutionizes disease tracking.
Biological Treatments for Crohn's Disease: Past and Present
Explore the evolution of biological treatments for Crohn's disease, from Remicade to the latest advancements. Discover targeted and effective solutions.
What's the Connection Between Gum Disease and IBD - Inflammatory Bowel Diseases?
Discover the surprising link between gum disease and IBD (Inflammatory Bowel Diseases). Uncover the complex connection and potential treatment approaches.
